| CAS NO: | 2752-64-9 |
| 包装: | 20mg |
| 市场价: | 1712元 |
| Cas No. | 2752-64-9 |
| 别名 | 中乌头碱；新乌头碱；美沙乌头碱；新乌碱 |
| 化学名 | 11a-acetoxy-4,9,11-trihydroxy-6,10,13-trimethoxy-3-(methoxymethyl)-1-methyltetradecahydro-1H-3,6a,12-(epiethane[1,1,2]triyl)-7,9-methanonaphtho[2,3-b]azocin-8-yl benzoate |
| Canonical SMILES | CC(O[C@]([C@@]1([H])[C@@](OC)([H])[C@]2([H])[C@@](COC)([C@@](O)([H])C[C@@](OC)([H])[C@@]32C14[H])CN4C)([C@](O)([H])[C@]5([H])OC)[C@]6([H])[C@@]3([H])C[C@@]5(O)[C@]6([H])OC(C7=CC=CC=C7)=O)=O |
| 分子式 | C33H45NO11 |
| 分子量 | 631.71 |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Mesaconitine is the main active component of genus aconitum plants.IC50 value:Target: in vitro: In HUVECs, 30 microM mesaconitine increased the [Ca(2+)](i) level in the presence of extracellular CaCl(2) and NaCl, and the response was inhibited by KBR7943. Mesaconitine increased intracellular Na(+) concentration level in HUVECs. The [Ca(2+)](i) response by mesaconitine was inhibited by 100 microM D-tubocurarine [1]. Mesaconitine at 30 microM inhibited 3 microM phenylephrine-induced contraction in the endothelium-intact, but not endothelium-denuded, aortic rings [2]. MA promoted the alpha-MT-induced decrease in NE levels in hippocampus, medulla oblongata plus pons and spinal cord [3]. References: |
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