CHK1-IN-3

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CHK1-IN-3

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2097252-39-4

包装与价格：

包装	价格(元)
100mg	电议
250mg	电议
500mg	电议

产品介绍

CHK1-IN-3 是一种检测点激酶(CHK1)抑制剂，IC₅₀值为 0.4 nM。

生物活性

CHK1-IN-3 is aCheckpoint Kinase 1 (CHK1)inhibitor with anIC₅₀of 0.4 nM^[1].

IC₅₀& Target^[1]

Chk1

0.4 nM (IC₅₀)

体外研究
(In Vitro)

CHK1-IN-3 effectively inhibites the growth of malignant hematopathy cell lines especially Z-138 (IC50: 0.013 μM) and displays low affinity for hERG (IC50 >40 μM)^[1].

体内研究
(In Vivo)

CHK1-IN-3 significantly suppresses the tumor growth in Z-138 cell inoculated xenograft model as a single agent with body weight unaffected^[1].

分子量

405.46

Formula

C₂₀H₂₃N₉O

CAS 号

2097252-39-4

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.