CDK4/6-IN-8

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CDK4/6-IN-8

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

2649120-22-7

包装与价格：

产品介绍

CDK4/6-IN-8 (Compound 7p) 是一种选择性的CDK4和CDK6抑制剂，其IC₅₀值分别为 5.01 nM 和 3.97 nM。

生物活性

CDK4/6-IN-8 (Compound 7p) is a selectiveCDK4andCDK6inhibitor withIC₅₀values of 5.01 nM and 3.97 nM, respectively^[1].

IC₅₀& Target

CDK4

5.01 nM (IC₅₀)

CDK6

3.97 nM (IC₅₀)

体外研究
(In Vitro)

CDK4/6-IN-8 (Compound 7p) (0-656.1 μM, 48 h) shows anti-breast cancer activity^[1].

Cell Viability Assay^[1]

Cell Line:	MCF-7
Concentration:	0.1, 0.3, 0.9, 2.7, 8.1, 24.3, 72.9, 218.7 and 656.1 μM
Incubation Time:	48 h
Result:	Inhibited cell viability with an IC₅₀of 2.8 μM.

分子量

398.37

Formula

C₁₈H₁₈N₆O₅

CAS 号

2649120-22-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.