| CAS NO: | 133865-89-1 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 50mg | 电议 |
| 500mg | 电议 |
| Cas No. | 133865-89-1 |
| 别名 | 沙芬酰胺; FCE 26743; EMD 1195686 |
| 化学名 | (2S)-2-[[4-[(3-fluorophenyl)methoxy]phenyl]methylamino]propanamide |
| Canonical SMILES | CC(C(=O)N)NCC1=CC=C(C=C1)OCC2=CC(=CC=C2)F |
| 分子式 | C17H19FN2O2 |
| 分子量 | 302.34 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Safinamide (FCE 26743) selectively and reversibly inhibits MAO-B with IC50 of 98 nM, exhibits 5918-fold selectivity against MAO-A[1]. Safinamide (FCE 26743) is a highly selective and reversible monoamine oxidase type B (MAO-B) inhibitor that increases neostriatal dopamine concentration. In addition, Safinamide (FCE 26743) is voltage-dependent sodium and calcium channel blocker. Safinamide (FCE 26743) appears to bind to the batrachotoxin-sensitive site 2 of the voltage-sensitive sodium channels. Safinamide blocks N and L-type calcium channels and inhibits glutamate and aspartate release from synaptic terminals[1]. References: |
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