NU-9056 (NU9056) is novel, potent and selective KAT5 (Tip60) histone acetyltransferase inhibitor with anticancer effects. It inhibits KAT5 with IC50 values of < 2, 60, 36, and >100 μM for KAT5, p300, pCAF and GCN5, respectively. Also inhibits protein acetylation in prostate cancer cell lines and blocks DNA damage response. It alsp decreases proliferation of LNCaP cells; induces apoptosis via caspase activation.

纯度：≥98%

CAS：1450644-28-6