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CK2 inhibitor 3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CK2 inhibitor 3图片
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
CK2 inhibitor 3 是一种有效的CK2抑制剂,IC50为 280 nM。CK2 inhibitor 3 可抑制细胞内的 CK2,显著影响肿瘤细胞的活力,并对一组 320 激酶显示出显著的选择性。
生物活性

CK2 inhibitor3 is a potentCK2inhibitor withIC50value of 280 nM.CK2 inhibitor3 inhibits endocellularCK2, significantly affects viability of tumour cells and shows remarkable selectivity on a panel of 320 kinases[1].

IC50& Target[1]

CK2

280 nM (IC50)

体外研究
(In Vitro)

CK2 inhibitor 3 (compound 4) (0-50 μM; 24 hours) significantly reduces cell viability in a dose-dependent manner, and DC50value is 12.80 μM[1].
CK2 inhibitor 3 (5 μM and 20 μM; 16 hours) decreases the CK2-dependent phospho-site Akt Ser129 level[1].

Cell Viability Assay

Cell Line:Jurkat cells[1]
Concentration:0 μM, 10 μM, 20 μM, 30 μM, 40 μM and 50 μM
Incubation Time:24 hours
Result:Significantly reduced cell viability in a dose-dependent manner, and DC50value was 12.80 μM.

Western Blot Analysis

Cell Line:Jurkat cells[1]
Concentration:5 μM and 20 μM
Incubation Time:16 hours
Result:Decreased the CK2-dependent phospho-site Akt Ser129 level.
分子量

381.20

Formula

C13H9BrN4O3S

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.