Adrenomedullin(AM)(22-52),human(22-52-Adrenomedullin(human))

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CAS NO:

159899-65-7

包装与价格：

产品介绍

Adrenomedullin (AM) (22-52), human (22-52-Adrenomedullin (human))，一种 NH2 末端截短的肾上腺髓质素类似物，是一种肾上腺髓质素受体拮抗剂，也拮抗后肢血管中的降钙素基因相关肽 (CGRP) 受体猫的床。

Cas No.	159899-65-7
别名	肾上腺髓质素(22-52)(人体),22-52-Adrenomedullin (human)
Canonical SMILES	Thr-Val-Gln-Lys-Leu-Ala-His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg-Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2
分子式	C₁₅₉H₂₅₂N₄₆O₄₈
分子量	3576.04
溶解度	Soluble in DMSO
储存条件	Store at -20°C
General tips	For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition	Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request
产品描述	Adrenomedullin (AM) (22-52), human is an adrenomedullin receptor antagonist, and also antagonizes the calcitonin generelated peptide (CGRP) receptor in the hindlimb vascular bed of the cat. Adrenomedullin (AM) (22-52), human shows no effect on hindlimb perfusion pressure responses to adrenomedullin (ADM) at 120 nmol. However, Adrenomedullin (AM) (22-52), human selectively and reversibly decreases vasodilator responses to human calcitonin generelated peptide (hCGRP) at 30 nmol, with similar effect to that of CGRP antagonist[1]. [1]. Champion HC, et al. Adrenomedullin-(22-52) antagonizes vasodilator responses to CGRP but not adrenomedullin in the cat. Am J Physiol. 1997 Jan;272(1 Pt 2):R234-42.