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Mn(III)TMPyP
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Mn(III)TMPyP图片
包装与价格:
包装价格(元)
10mg电议
25mg电议
50mg电议
100mg电议

产品介绍
化学名Mn(III)tetrakis(1-methyl-4-pyridyl)porphyrin pentachloride
Canonical SMILESC[n]1ccc(cc1)C1=c2ccc3C(=c4ccc5=C(c6cc[n](C)cc6)c6ccc7=C(c8cc[n](C)cc8)c8ccc1n8[Mn]([n]23)([n]67)n45)c1cc[n](C)cc1
分子式C44H36MnN8o 5Cl
分子量909
溶解度Soluble at concentration of at least 50mg/mL in 0.1 M Tris-HCI buffer (1 mM EDTA, pH 9.0), and 4mg/mL in PBS (pH 7.2)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Mn(III)TMPyP is a manganese-porphyrin which acts as a superoxide dismutase (SOD) mimetic and peroxynitrite decomposition catalyst. SOD mimetics described to date are unstable and are capable of catalyzing undesired side-reactions in addition to the dismutation of the superoxide radical (O2-). Mn(III)TMPyP is an SOD mimetic with increased stability to pH and hydrogen peroxide. The rate constant for superoxide dismutation and peroxynitrite decomposition are 3.9 x 107 M-1s-1 and ~2 x 106 M-1s-1, respectively. Mn(III)TMPyP protected and enhanced the growth of SOD null E. coli with a doubling time of 60 minutes (as compared to 240 minutes of the control) at 25 &#181M.