Ammonium iron(III)citrate

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本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

CAS NO:

1185-57-5

包装与价格：

包装	价格(元)
1 g	电议
5 g	电议
10 g	电议

产品名称

柠檬酸铁 (III) 铵
Ammonium ferric citrate
FAC

产品介绍

Ammonium iron(III) citrate (Ammonium ferric citrate) 是一种非运铁蛋白结合的铁的生理形式，会引起的细胞内铁超负荷从而导致细胞铁死亡 (ferroptosis)。Ammonium iron(III) citrate 可以增强蛋白质的产生。

生物活性

Ammonium iron(III) citrate (Ammonium ferric citrate), a physiological form of nonetransferrin-bound iron, induces intracellular iron overload to causeferroptosis^[1]. Ammonium iron(III) citrate can enhance protein production^[2].

体外研究
(In Vitro)

Ammonium iron(III) citrate (Ammonium ferric citrate; 1, 5, 10, 15 mM; 24 hours) with 5 mM induces cell death in HT1080 cells. AML12 cells were highly resistant to Ammonium iron(III) citrate, as they maintained cell viability about 80%. Ammonium iron(III) citrate can be actively transported into cells by specific transporter^[1].
Ammonium iron(III) citrate (6, 12, 18 mg/L) has a higher biomas forChlorella vulgarisFSP-E (CV) in BG-11 medium with 12 mg/L and 18 mg/L^[2].

Clinical Trial

性状

Solid

Formula

C₆H₈O₇.xFe.xH₃N

CAS 号

1185-57-5

中文名称

柠檬酸铁 (III) 铵

结构分类

Ketones, Aldehydes, Acids

来源

Plants
Rutaceae
Citrus reticulataBlanco

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据

In Vitro:

H₂O : 33.33 mg/mL(Need ultrasonic)

DMSO :< 1 mg/mL (ultrasonic)(insoluble or slightly soluble)

In Vivo:

请根据您的实验动物和给药方式选择适当的溶解方案。以下溶解方案都请先按照In Vitro方式配制澄清的储备液，再依次添加助溶剂：

——为保证实验结果的可靠性，澄清的储备液可以根据储存条件，适当保存；体内实验的工作液，建议您现用现配，当天使用；以下溶剂前显示的百
分比是指该溶剂在您配制终溶液中的体积占比；如在配制过程中出现沉淀、析出现象，可以通过加热和/或超声的方式助溶

1.
请依序添加每种溶剂： PBS
Solubility: 50 mg/mL (Infinity mM); Clear solution; Need ultrasonic

*以上所有助溶剂都可在本网站选购。