(E)-Ferulic acid-d3 ((E)-Coniferic acid-d3) is the deuterium labeled (E)-Ferulic acid. (E)-Ferulic acid is a isomer of Ferulic acid which is an aromatic compound, abundant in plant cell walls. (E)-Ferulic acid causes the phosphorylation ofβ-catenin, resulting in proteasomal degradation ofβ-cateninand increases the expression of pro-apoptotic factorBaxand decreases the expression of pro-survival factorsurvivin. (E)-Ferulic acid shows a potent ability to removereactive oxygen species(ROS) and inhibits lipid peroxidation. (E)-Ferulic acid exerts both anti-proliferation and anti-migration effects in the human lungcancercell line H1299^[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

197.20

Solid

C₁₀H₇D₃O₄

860605-59-0

反式-阿魏酸 d3

Room temperature in continental US; may vary elsewhere.