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Salicyl-AMS
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Salicyl-AMS图片
CAS NO:863238-55-5
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
1mg电议
5mg电议
10mg电议

产品介绍
Salicyl-AMS是可以抑制分支杆菌生长素生物合成的抑制剂,且在体外缺铁定的条件下能抑制结核分枝杆菌的生长。
Cas No.863238-55-5
Canonical SMILESO[C@@H]1[C@@H](COS(=O)(NC(C2=C(O)C=CC=C2)=O)=O)O[C@@H](N3C(N=CN=C4N)=C4N=C3)[C@@H]1O
分子式C17H18N6O8S
分子量466.43
溶解度DMSO : ≥ 90.5 mg/mL (194.03 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Salicyl-AMS is a mycobactin biosynthesis inhibitor which can also inhibit M. tuberculosis growth in vitro under iron-limited conditions.

[1]. Lun S, et al. Pharmacokinetic and in vivo efficacy studies of the mycobactin biosynthesis inhibitor salicyl-AMS in mice. Antimicrob Agents Chemother. 2013 Oct;57(10):5138-40. [2]. Ferreras JA, et al. Small-molecule inhibition of siderophore biosynthesis in Mycobacterium tuberculosis and Yersinia pestis. Nat Chem Biol. 2005 Jun;1(1):29-32.