Cas No. | 35900-16-4 |
别名 | 前列腺素EP杂质I |
化学名 | 11α,15S-dihydroxy-9-oxo-prost-13E-en-1-oic acid, ethyl ester |
Canonical SMILES | O=C1[C@H](CCCCCCC(OCC)=O)[C@@H](/C=C/[C@@H](O)CCCCC)[C@H](O)C1 |
分子式 | C22H38O5 |
分子量 | 382.5 |
溶解度 | DMF: 50 mg/ml,DMSO: 50 mg/ml,Ethanol: 30 mg/ml,PBS (pH 7.2): 0.25 mg/ml |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Prostaglandin E1 (PGE1) is the theoretical cyclooxygenase metabolite of dihomo-γ-linolenic acid. Its pharmacology includes vasodilation, hypotension, and anti-platelet activities. The IC50 value of PGE1 for the inhibition of ADP-induced human platelet aggregation is 40 nM. PGE1 is used to treat male erectile dysfunction and to maintain ductus arteriosus patency in infants. PGE1 ethyl ester is an esterified form of the free acid which may be more amenable for certain applications. |