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CAY10599
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
CAY10599图片
CAS NO:1143573-33-4
包装与价格:
包装价格(元)
500µg电议
1mg电议
5mg电议
10mg电议

产品介绍
Cas No.1143573-33-4
化学名2-[[1-[3-[4-([1,1'-biphenyl]-4-ylcarbonyl)-2-propylphenoxy]propyl]-1,2,3,4-tetrahydro-5-quinolinyl]oxy]-2-methyl-propanoic acid
Canonical SMILESCC(C)(C(O)=O)OC1=CC=CC2=C1CCCN2CCCOC3=CC=C(C(C4=CC=C(C5=CC=CC=C5)C=C4)=O)C=C3CCC
分子式C38H41NO5
分子量591.7
溶解度DMF: 25 mg/ml,DMSO: 25 mg/ml,Ethanol: 25 mg/ml
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述 Thiazolidinediones (TZDs) are a group of structurally related peroxisome proliferator-activated receptor γ (PPARγ) agonists with antidiabetic actions in vivo. The prototypical compound for this class is the TZD rosiglitazone (BRL 49653), which is currently marketed for the treatment of diabetes. CAY10599 is a PPARγ agonist that is 4-fold more potent than rosiglitazone at the PPARγ receptor demonstrating an EC50 value of 0.05 uM. This compound shows high selectivity for PPARγ over PPARα (EC50 = 3.99 uM) or PPARδ (EC50 >10 uM).