| CAS NO: | 33068-19-8 |
| 包装 | 价格(元) |
| 10mg | 电议 |
| 25mg | 电议 |
| 50mg | 电议 |
| 100mg | 电议 |
A synthetic analog of glucose used in cell metabolism and cancer research
| Cas No. | 33068-19-8 |
| 别名 | 2-脱氧-D-葡萄糖-6-磷酸钠盐,2-Deoxyglucose-6-phosphate |
| 化学名 | 6-(dihydrogen phosphate) 2-deoxy-D-arabino-hexose, monosodium salt |
| Canonical SMILES | O=CC[C@@H](O)[C@H](O)[C@H](O)COP(O)([O-])=O.[Na+] |
| 分子式 | C6H12O8P o Na |
| 分子量 | 266.1 |
| 溶解度 | 10 mg/ml in PBS (pH 7.2) |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | 2-deoxy-D-Glucose is a synthetic analog of glucose used in cell metabolism and cancer research.[1] 2-deoxy-D-Glucose-6-phosphate (2-DG6P) is a derivative of 2-DG. It is produced in mammalian cells by the action of hexokinase on 2-DG. The accumulation of 2-DG6P in cells can inhibit glycolysis, leading to cell death.[2] However, the uptake of 2-DG by cells can be monitored in assays by the accumulation of 2-DG6P, which can be oxidized in vitro by glucose 6-phosphate dehydrogenase and reduce NADP+. In bacteria and yeast, 2-DG6P is metabolized to 2-DG by 2-DG6P phosphatase. Reference |
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