CAS NO: | 1260092-44-1 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
1 g | 电议 |
5 g | 电议 |
生物活性 | Boc-NH-PEG1-CH2CH2COOH is acleavable(1 unit PEG)ADC linkerand also aPEG- andAlkyl/ether-basedPROTAClinkercan be used in the synthesis ofantibody-drug conjugates (ADCs)orPROTACs[1][2]. | ||||||||||||
IC50& Target[1] |
| ||||||||||||
体外研究 (In Vitro) | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1]. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. | ||||||||||||
分子量 | 233.26 | ||||||||||||
性状 | Solid | ||||||||||||
Formula | C10H19NO5 | ||||||||||||
CAS 号 | 1260092-44-1 | ||||||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||||||
储存方式 |
|