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15-OxoEDE
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
15-OxoEDE图片
CAS NO:105835-44-7
包装与价格:
包装价格(元)
25μg电议
50μg电议
100μg电议
250μg电议

产品介绍
Cas No.105835-44-7
Canonical SMILESCCCCCC(=O)/C=C\C=C\CCCCCCCCCC(=O)O
分子式C20H34O3
分子量322.5
溶解度DMF: >50 mg/ml (per Rao Maddipati),DMSO: >50 mg/ml (per Rao Maddipati),Ethanol: >50 mg/ml (per Rao Maddipati),PBS pH 7.2: >1 mg/ml (from 13(S)-HODE)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

15-OxoEDE is produced by the oxidation of 15-HEDE. 15-OxoEDE inhibits 5-LO from RBL-1 cells with an IC50 of 55 µM, which is about 2-fold lower than 15(S)-HEDE. A related oxo-eicosanoid, 5-oxoETE, is biosynthesized from 5(S)-HETE by a specific dehydrogenase and has potent inflammatory activity.