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Bromoacetamido-PEG4-acid
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Bromoacetamido-PEG4-acid图片
CAS NO:1807518-67-7
包装与价格:
包装价格(元)
50mg电议
100mg电议
250mg电议
500mg电议
1 g电议

产品介绍
Bromoacetamido-PEG4-acid 是一种 PROTAC linker,属于 PEG 类。可用于合成PROTAC分子。Bromoacetamido-PEG4-acid 也是一种可降解 (cleavable) 的含 4 个单元 PEG 的 ADC linker,可用于合成抗体偶联药物 (ADC)。
生物活性

Bromoacetamido-PEG4-acid is a PEG-basedPROTAClinker that can be used in the synthesis ofPROTACs[1]. Bromoacetamido-PEG4-acid is also acleavable4 unit PEGADC linkerused in the synthesis ofantibody-drug conjugates (ADCs)[2].

IC50& Target

PEGs

 

Cleavable

 

体外研究
(In Vitro)

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[2].

分子量

386.24

性状

Viscous liquid

Formula

C13H24BrNO7

CAS 号

1807518-67-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Pure form-20°C3 years
4°C2 years
In solvent-80°C6 months
-20°C1 month