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Maytansinoid DM4
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Maytansinoid DM4图片
CAS NO:799840-96-3
包装与价格:
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
Maytansinoid DM4 是一种具有强力细胞毒性的含硫醇美登素衍生物,可用作 ADC 毒性分子。
生物活性

Maytansinoid DM4 is a thiol-containing maytansine derivative with highly potent cytotoxicity. Maytansinoid DM4 can be used as a cytotoxic moiety of ADC[1][2].

IC50& Target[1][2]

Maytansinoids

 

体外研究
(In Vitro)

Maytansine is a natural benzoansamacrolide product isolated from the bark of the African shrubMaytenus ovatus. Maytansine binds to the same site on tubulin as the vinca alkaloids, with similar in vitro inhibition constants, but is a more-potent cytotoxin[1].

分子量

794.39

Formula

C39H56ClN3O10S

CAS 号

799840-96-3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.