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Oxybutynin chloride
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Oxybutynin chloride图片
CAS NO:1508-65-2
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
100mg电议

产品介绍
Oxybutynin chloride 是一种口服活性的竞争性 mAChR 拮抗剂,在小鼠膀胱和大脑皮层中特异性结合 [3H]NMS 的 Kis 分别为 14.3 和 5.55 nM。
Cas No.1508-65-2
别名盐酸奥昔布宁
化学名4-(diethylamino)but-2-ynyl 2-cyclohexyl-2-hydroxy-2-phenylacetate;hydrochloride
Canonical SMILESCCN(CC)CC#CCOC(=O)C(C1CCCCC1)(C2=CC=CC=C2)O.Cl
分子式C22H32ClNO3
分子量393.95
溶解度≥ 19.7mg/mL in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Oxybutynin chloride is an anticholinergic agent, which inhibits vascular Kv channels in a concentration-dependent manner, with an IC50 of 11.51 μM[1].

References:
[1]. Li H, The anticholinergic drug oxybutynin inhibits voltage-dependent K+ channels in coronary arterial smooth muscle cells. Clin Exp Pharmacol Physiol. 2019 Nov;46(11):1030-1036.