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Tetracaine HCl
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tetracaine HCl图片
CAS NO:136-47-0
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
50mg电议

产品介绍
Anaesthetic and allosteric inhibitor
Cas No.136-47-0
别名盐酸丁卡因,Amethocaine hydrochloride
化学名2-(dimethylamino)ethyl 4-(butylamino)benzoate;hydrochloride
Canonical SMILESCCCCNC1=CC=C(C=C1)C(=O)OCCN(C)C.Cl
分子式C15H24N2O2.HCl
分子量300.82
溶解度≥ 10.85mg/mL in DMSO
储存条件Store at -20°C,unstable in solution, ready to use.
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Tetracaine hydrochloride (Amethocaine hydrochloride) is a potent local anaesthetic and a channel function allosteric inhibitor.Target: Calcium ChannelTetracaine hydrochloride (Amethocaine hydrochloride) is a calcium channel protein inhibitor and blocks voltage-sensitive release of Ca2+ from sarcoplasmic reticulum. Tetracaine hydrochloride (Amethocaine hydrochloride) is a potent local anesthetic of the ester group. It is mainly used topically in ophthalmology and as an antipruritic, and it has been used in spinal anesthesia. Tetracaine hydrochloride (Amethocaine hydrochloride) is used to alter the function of calcium release channels (ryanodine receptors) that control the release of calcium from intracellular stores. Tetracaine hydrochloride (Amethocaine hydrochloride) is an allosteric blocker of channel function. At low concentrations, tetracaine causes an initial inhibition of spontaneous calcium release events, while at high concentrations, tetracaine blocks release completely [1, 2].

References:
[1]. http://en.wikipedia.org/wiki/Tetracaine
[2]. http://www.ncbi.nlm.nih.gov/pubmed/9147318