Setosusin ((+)-Setosusin) 是一种真菌类二萜,具有独特的螺融合 3(2H)-呋喃酮部分。
Cas No. | 182926-45-0 |
别名 | (+)-Setosusin |
Canonical SMILES | CC([C@@]1([H])[C@@]([C@@H](OC(C)=O)C2)(C)[C@]3([H])[C@@]([C@]4(C[C@@]5(C(C(C)=C(C)O5)=O)C(O4)=O)C(C)=CC3)(C)CC1)(C)OC2=O |
分子式 | C29H38O8 |
分子量 | 514.6 |
溶解度 | Soluble in DMSO |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Setosusin is a meroterpenoid fungal metabolite originally isolated from C. setosus. It reduces neurotoxicity induced by amyloid-β (Aβ) aggregates in PC12 cells (EC50 = 112.6 μM). In vivo, setosusin (30 mg/kg) induces tremors in mice. |