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WSP-5
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
WSP-5图片
CAS NO:1593024-78-2
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
Cas No.1593024-78-2
别名Washington State Probe-5
化学名3-oxo-3H-spiro[isobenzofuran-1,9'-xanthene]-3',6'-diyl bis(2-(pyridin-2-yldisulfanyl)benzoate)
Canonical SMILESO=C(OC1=CC=C2C(OC3=C(C24C5=CC=CC=C5C(O4)=O)C=CC(OC(C6=CC=CC=C6SSC7=CC=CC=N7)=O)=C3)=C1)C8=C(SSC9=NC=CC=C9)C=CC=C8
分子式C44H26N2O7S4
分子量822.9
溶解度25 mg/ml in DMSO, 30 mg/ml in DMF
储存条件Store at -20°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
文献引用
产品描述

Hydrogen sulfide (H2S) is an important gaseous mediator, like nitric oxide, that has significant effects on the immunological, neurological, cardiovascular and pulmonary systems of mammals. WSP-5 is a reactive disulfide-containing, fluorescent probe designed for fast detection of H2S in biological samples and cells. Through a reaction-based fluorescent turn-on strategy, WSP-5 selectively and rapidly reacts with H2S, generating a fluorophore with excitation and emission maxima of 502 and 525 nm, respectively. WSP-5 demonstrates a faster fluorescence turn-on rate (60- vs. 130-fold) and a more sensitive detection limit (47 vs. 60 nM) toward H2S compared to WSP-1 .

Reference:
[1]. Peng, B., Chen, W., Liu, C., et al. Fluorescent probes based on nucleophilic substitution-cyclization for hydrogen sulfide detection and bioimaging. Chemistry 20(4), 1010-1016 (2014).