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&beta-Chloro-L-alanine(L-&beta-Chloroalanine)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
&beta-Chloro-L-alanine(L-&beta-Chloroalanine)图片
CAS NO:2731-73-9
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
100mg电议

产品介绍
β-Chloro-L-alanine (L-β-Chloroalanine) 是一种抑菌氨基酸类似物,可抑制多种酶,包括苏氨酸脱氨酶和丙氨酸消旋酶。
Cas No.2731-73-9
别名3-氯-L-丙氨酸,L-β-Chloroalanine
Canonical SMILESOC([C@@H](N)CCl)=O
分子式C3H6ClNO2
分子量123.54
溶解度Water : ≥ 30 mg/mL (242.84 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

β-Chloro-L-alanine is a bacteriostatic amino acid analog which inhibits a number of enzymes, including threonine deaminase and alanine racemase.

β-Chloro-L-alanine can inhibit threonine deaminase, the branched-chain amino acid transaminase (transaminase B), L-aspartate-pdecarboxylase, alanine racemase and probably O-acetylserine sulfhydrylase. β-Chloro-L-alanine reversibly inhibits the Escherichia coli K-12 alanine-valine transaminase, transaminase C. This inhibition, along with the inhibition of transaminase B, account for the isoleucine-plus-valine requirement of Escherichia coli in the presence of β-Chloro-L-alanine. Salmonella typhimurium LT2 will grow in the presence of BCA if isoleucine and valine are added to the medium and presume that the growth requirement is due to the inhibition of transaminase B[1].

[1]. β-Chloro-L-alanine can inhibits threonine deaminase, the branched-chain amino acid transaminase (transaminase B), L-aspartate-pdecarboxylase, alanine racemase and probably O-acetylserine sulfhydrylase. β-Chloro-L-alanine reversibly inhibits the Escherichia coli