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WQ3810(KPI-10 free base)
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
WQ3810(KPI-10 free base)图片
CAS NO:888032-58-4
包装与价格:
包装价格(元)
1mg电议
5mg电议
10mg电议

产品介绍
WQ3810 (KPI-10 free base) 是一种具有口服活性的氟喹诺酮类药物,具有有效的抗菌活性。
Cas No.888032-58-4
别名KPI-10 free base
Canonical SMILESO=C(C1=CN(C2=NC(N)=C(F)C=C2F)C3=C(C=C(F)C(N4CC(NC(C)C)C4)=C3C)C1=O)O
分子式C22H22F3N5O3
分子量461.44
溶解度Soluble in DMSO
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

WQ3810 is an orally active fluoroquinolone, with potent antibacterial activities.

WQ-3810 shows potent activity against A. baumannii, including MDR isolates, with MIC90 of 1 mg/L, more than eight-fold higher than that of ciprofloxacin (64 mg/L) and levofloxacin (8 mg/L). WQ-3810 also exhibits inhibitory effects on E. coli and S. pneumoniae, including FQR isolates, with MIC90 of 4 mg/L and 0.06 mg/L, respectively. WQ-3810 is the most potent among the fluoroquinolones tested against meticillin-resistant Staphylococcus aureus (MRSA) and Neisseria gonorrhoeae, including FQR isolates[1].

[1]. Kazamori D, et al. In vitro activity of WQ-3810, a novel fluoroquinolone, against multidrug-resistant and fluoroquinolone-resistant pathogens. Int J Antimicrob Agents. 2014 Nov;44(5):443-9.