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AN3199
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
AN3199图片
CAS NO:1187187-10-5
包装与价格:
包装价格(元)
10mM (in 1mL DMSO)电议
1mg电议
5mg电议
10mg电议
25mg电议
50mg电议

产品介绍
AN3199是一种PDE4抑制剂,IC50为94.5nM。
Cas No.1187187-10-5
Canonical SMILESO=C(C1=CC=C(OC2=CC=C(B(O)OC3)C3=C2)N=C1)OCCCC
分子式C17H18BNO5
分子量327.14
溶解度DMSO : 100 mg/mL (305.68 mM)
储存条件Store at -20°C
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

AN3199 is a PDE4 inhibitor with IC50 of 94.5 nM.IC50 value: 94.5 nM [1]Target: PDE4The detailed information please refer to Compound 11 in the reference.

[1]. Zhang YK, et al. Design and synthesis of boron-containing PDE4 inhibitors using soft-drug strategy for potential dermatologic anti-inflammatory application. Bioorg Med Chem Lett. 2010 Apr 1;20(7):2270-4. [2]. Akama Tsutomu, et al. Preparation of boron-containing small molecules as anti-inflammatory agents. From PCT Int. Appl. (2009), WO 2009111676 A2 20090911.