Mitoxantrone-d8 (mitozantrone-d8) is the deuterium labeled Mitoxantrone. Mitoxantrone is atopoisomeraseIIinhibitor and also inhibits protein kinase C (PKC) activity with anIC₅₀of 8.5 μM^[1][2].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

452.53

C₂₂H₂₀D₈N₄O₆

1189974-82-0

米托蒽醌 d8

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.