9(S)-HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase (5-LO) on α-linolenic acid.
Cas No. | 111004-08-1 |
Canonical SMILES | CC/C=C\C/C=C\C=C\[C@@H](OO)CCCCCCCC(O)=O |
分子式 | C18H30O4 |
分子量 | 310.4 |
溶解度 | DMF: >50 mg/ml (from 13(S)-HODE),DMSO: >50 mg/ml (from 13(S)-HODE),Ethanol: >50 mg/ml (from 13(S)-HODE),PBS pH 7.2: >1 mg/ml (from 13(S)-HODE) |
储存条件 | Store at -20℃, protect from light |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | 9(S)-HpOTrE is a monohydroperoxy polyunsaturated fatty acid produced by the action of 5-lipoxygenase (5-LO) on α-linolenic acid. It can be further metabolized to colnelenic acid by a divinyl ether synthase activity found in garlic and potato microsomal fractions. 9(S)-HpOTrE also serves as a substrate for further oxidation by both soybean and potato LOs, resulting in the formation of 9,16-dihydroperoxy acid. The suicide inactivation of LOs when 9(S)-HpOTrE is used as a substrate is thought to occur via formation of an unstable epoxide. |