| CAS NO: | 1404-15-5 |
| 包装 | 价格(元) |
| 1mg | 电议 |
| 5mg | 电议 |
| 10mg | 电议 |
| 生物活性 | Nogalamycin is an anthracyclinoneantibiotic. Nogalamycin is a potentantibioticagainst Gram-positive bacteria, also has cytotoxicity against certain tumor cells. Nogalamycin is produced byStreptomyces nogalater var. Nogalater. Nogalamycin selectively inhibits RNA synthesis after binding to DNA template. Nogalamycin can be used for researching anticancer[1][2]. | |||||||||
| IC50& Target | RNA Synthesis[2] | |||||||||
| 体外研究 (In Vitro) | Nogalamycin (0-10 μg/ml; 2 hours) exhibits lethality against CHO, L1210 and B16 with LD50s of 2.74 μg/ml, 0.25 μg/ml and 0.15 μg/ml[1]. Cell Cytotoxicity Assay
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| 体内研究 (In Vivo) | Nogalamycin (0-1000 mug/kg; IP) can regress chemically-induced fibrosarcoma tumors and tumors of spontaneous origin in rats[3].
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| 分子量 | 787.80 | |||||||||
| 性状 | Solid | |||||||||
| Formula | C39H49NO16 | |||||||||
| CAS 号 | 1404-15-5 | |||||||||
| 运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||
| 储存方式 |
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