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Karacoline
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Karacoline图片
CAS NO:39089-30-0
包装:20mg
市场价:4263元

产品介绍
Karacoline 是一种在植物乌头中发现的二萜生物碱,通过 NF-κB 信号通路减少椎间盘退变 (IDD) 中细胞外基质 (ECM) 的降解。
Cas No.39089-30-0
别名多根乌头碱
Canonical SMILESCCN1CC2(CCC(C34C2CC(C31)C5(CC(C6CC4C5C6O)OC)O)O)C
分子式C22H35NO4
分子量377.52
储存条件4°C, protect from light
General tipsFor obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping ConditionEvaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
产品描述

Karacoline, a diterpene alkaloid found in the plant Aconitum kusnezoffii, reduces degradation of the extracellular matrix (ECM) in intervertebral disc degeneration (IDD) via the NF-κB signaling pathway[1].

References:
[1]. XiaoliZhou, et al. Karacoline, identified by network pharmacology, reduces degradation of the extracellular matrix in intervertebral disc degeneration via the NF-κB signaling pathway. Journal of Pharmaceutical Analysis, 2019.