Balofloxacin (Q-35) is an orally active fluoroquinoloneantibioticwith broad-spectrum antibacterial activity against gram-negative, gram-positive, and anaerobic bacteria. Balofloxacin can be used for the research of respiratory, intestinal, and urinary tract infections^[1][2].

Balofloxacin (25 mg/mL; 1 h) decreases the growth of S.aureusthat adhered to human corneal epithelial cells (HCECs)^[2].
Balofloxacin inhibits the S.aureusATCC 25923, with a MIC of 0.125 mg/mL^[2].
Balofloxacin (0.05-500 μg/mL; 72 h) does not induce toxicity on the HCECs at a low concentration, such as 0.625 mg/mL^[2].

Balofloxacin (200 mg/kg/day; p.o. for 5 d) reduces the counts of viableM. pneumoniain the lungs of hamsters^[3].
Balofloxacin eye drops (0.5%) is effective in S. aureus bacterial keratitis of rabbits^[2].

389.42

Solid

C₂₀H₂₄FN₃O₄

127294-70-6

巴洛沙星

Room temperature in continental US; may vary elsewhere.

DMSO : 0.67 mg/mL(1.72 mM;Need ultrasonic)

H₂O : 0.67 mg/mL(1.72 mM;Need ultrasonic)

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储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。