Direct Violet 1, an azo dye, is a textile dye. Direct Violet 1 is also the protein-protein interaction (PPI) between theSARS-CoV-2 spike proteinandACE2inhibitor withIC₅₀s of 1.47-2.63 μM^[1][2].

IC50: 1.47 μM (SARS-CoV-2-S-RBD binding to ACE2); 2.63 μM (SARS-CoV-S1S2 binding to ACE2); 2.11 μM (TNF-R1-TNFα binding)^[1]

Direct Violet 1 inhibits SARS-CoV-2-S-RBD binding to human ACE2, inhibits SARS-CoV-S1S2 binding to ACE2, and inhibits TNF-R1 binding to TNFα with IC₅₀values of 1.47 μM, 2.63 μM, and 2.11 μM, respectively^[1].
Direct Violet 1 inhibits SARS-CoV-2 pseudovirus entry into hACE2 expressing host cells in a concentration-dependent manner with an IC₅₀of 35.8 μM^[1].

728.66

Solid

C₃₂H₂₂N₆Na₂O₈S₂

2586-60-9

直接青莲N；直接紫1；直接紫N

Room temperature in continental US; may vary elsewhere.

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

H₂O : 62.5 mg/mL(85.77 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (sealed storage, away from moisture)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。