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Canthaxanthin
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Canthaxanthin图片
CAS NO:514-78-3
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议
200mg电议
500mg电议

产品名称
斑蝥黄
E 161g
all-trans-Canthaxanthin
产品介绍
Canthaxanthin是具有多种生物活性的红橙色类胡萝卜素,如抗氧化,抗肿瘤活性。
生物活性

Canthaxanthin is a red-orange carotenoid with various biological activities, such as antioxidant, antitumor properties.

IC50& Target

Human Endogenous Metabolite

 

体外研究
(In Vitro)

Canthaxanthin enrichment of LDL has the potential to protect cholesterol from oxidation. In addition to its free radical scavenging and antioxidant properties (e.g., the induction of catalase and superoxide dismutase), canthaxanthin shows immunomodulatory activity (e.g. enhancing the proliferation and function of immune competent cells) and plays important role in gap junction communication (e.g. induction of the transmembrane protein connexin)[1]. At concentrations of 0.1 to 1 x 1000 μM, canthaxanthin significantly reduces the overall number of tumor cells. The greatest inhibition is observed at a canthaxanthin concentration of 1000 after 72 h and 96 h of incubation[2].

体内研究
(In Vivo)

Canthaxanthin alters the protective ability of tissues against oxidative stress. Canthaxanthin treatment for 15 d at the dose of 14 μg/kg body weight results in hepatic incorporation of the carotenoid, which is maximum in liver and reaches 0.52 ± 0.05 nmol/g liver. Glutathione peroxidase activity is 35% lower and catalase (59%) and manganese superoxide dismutase (28%) activities are higher in canthaxanthin-treated mice than in controls[3]. Canthaxanthin inhibit the growth of mammary tumors in mice and the anti-tumor activity is also influenced by the supplemental dose[4]. Diet supplementation with canthaxanthin for 3 weeks prior to the carcinogen results in a 65% reduction in the number of mammary cancers by a mechanism not involving pro-vitamin A activity[5].

分子量

564.84

性状

Solid

Formula

C40H52O2

CAS 号

514-78-3

中文名称

角黄素;斑蝥黄质;斑蝥黄;裸藻酮

结构分类
  • Terpenoids
  • Other Terpenoids
来源

extremely halophilic bacteria

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, protect from light, stored under nitrogen

*该产品在溶液状态不稳定,建议您现用现配,即刻使用。

溶解性数据
In Vitro: 

DMSO : 1 mg/mL(1.77 mM;ultrasonic and warming and heat to 80℃)

H2O : 1 mg/mL(1.77 mM;ultrasonic and warming and heat to 80℃)

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM1.7704 mL8.8521 mL17.7041 mL
5 mM---------
10 mM---------
*

请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液;该产品在溶液状态不稳定,建议您现用现配,即刻使用