CAS NO: | 154523-54-3 |
包装 | 价格(元) |
1mg | 电议 |
5mg | 电议 |
10mg | 电议 |
生物活性 | Diclofenac-d4 sodium is the deuterium labeled Diclofenac sodium. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as aCOXinhibitor, withIC50s of 4 and 1.3 nM for humanCOX-1andCOX-2in CHO cells[1], and 5.1 and 0.84 μM for ovineCOX-1andCOX-2, respectively[2]. Diclofenac Sodium inducesapoptosisof neural stem cells (NSCs) via the activation of thecaspasecascade[3]. |
体外研究 (In Vitro) | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
分子量 | 322.16 |
性状 | Solid |
Formula | C14H6D4Cl2NNaO2 |
CAS 号 | 154523-54-3 |
中文名称 | 双氯芬酸钠 d4 (钠盐) |
运输条件 | Room temperature in continental US; may vary elsewhere. |
储存方式 | 4°C, sealed storage, away from moisture *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture) |