CAS NO: | 1161070-49-0 |
包装: | 5mg |
市场价: | 7800元 |
生物活性 | Trimethylamine N-oxide-d9 is the deuterium labeled Trimethylamine N-oxide. Trimethylamine N-oxide is a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients. Trimethylamine N-oxide induces inflammation by activating theROS/NLRP3 inflammasome. Trimethylamine N-oxide also accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis by activating theTGF-β/smad2signaling pathway[1][2][3]. | |||||||||
体外研究 (In Vitro) | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. | |||||||||
分子量 | 84.17 | |||||||||
性状 | Solid | |||||||||
Formula | C3D9NO | |||||||||
CAS 号 | 1161070-49-0 | |||||||||
中文名称 | 三甲胺N-氧化物 d9 | |||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | |||||||||
储存方式 |
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