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L-Phenylalanine-d2
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
L-Phenylalanine-d2图片
CAS NO:221346-31-2
包装与价格:
包装价格(元)
5mg电议
10mg电议
50mg电议
100mg电议

产品名称
(S)-2-Amino-3-phenylpropionic acid-d2
产品介绍
L-Phenylalanine-d2 ((S)-2-Amino-3-phenylpropionic acid-d2) 是 L-Phenylalanine 的氘代物。L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) 是分离自大肠杆菌的必需氨基酸。L-Phenylalanine 是一种电压依赖性 α2δ 亚基Ca2+通道拮抗剂,Ki为 980 nM。L-Phenylalanine 是NMDARs(KB573 μM) 和非NMDARs的甘氨酸和谷氨酸结合位点的竞争性拮抗剂。L-Phenylalanine 广泛用于食品香料和药品的生产中。
生物活性

L-Phenylalanine-d2 ((S)-2-Amino-3-phenylpropionic acid-d2) is the deuterium labeled L-Phenylalanine. L-Phenylalanine ((S)-2-Amino-3-phenylpropionic acid) is an essential amino acid isolated fromEscherichia coli. L-Phenylalanine is aα2δ subunit of voltage-dependent Ca+channelsantagonist with aKiof 980 nM. L-phenylalanine is a competitive antagonist for the glycine- and glutamate-binding sites ofN-methyl-D-aspartate receptors (NMDARs)(KBof 573 μM ) andnon-NMDARs, respectively. L-Phenylalanine is widely used in the production of food flavors and pharmaceuticals[1][2][3][4].

IC50& Target

NMDA Receptor

 

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

167.20

性状

Solid

Formula

C9H9D2NO2

CAS 号

221346-31-2

中文名称

L-苯丙氨酸 d2

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder-20°C3 years
4°C2 years
In solvent-80°C6 months
-20°C1 month
溶解性数据
In Vitro: 

DMSO : 2.5 mg/mL(14.95 mM;ultrasonic and warming and heat to 60℃)

配制储备液
浓度溶剂体积质量1 mg5 mg10 mg
1 mM5.9809 mL29.9043 mL59.8086 mL
5 mM1.1962 mL5.9809 mL11.9617 mL
10 mM0.5981 mL2.9904 mL5.9809 mL
*

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80℃, 6 months; -20℃, 1 month。-80℃ 储存时,请在 6 个月内使用,-20℃ 储存时,请在 1 个月内使用。