CAS NO: | 89-00-9 |
包装 | 价格(元) |
10mM (in 1mL DMSO) | 电议 |
1g | 电议 |
Cas No. | 89-00-9 |
别名 | 喹啉酸 |
化学名 | pyridine-2,3-dicarboxylic acid |
Canonical SMILES | OC(C1=CC=CN=C1C(O)=O)=O |
分子式 | C7H5NO4 |
分子量 | 167.12 |
溶解度 | ≥ 7.8mg/mL in DMSO |
储存条件 | Store at RT |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | Quinolinic acid is an endogenous N-methyl-D-aspartate (NMDA) receptor agonist synthesized from L-tryptophan via the kynurenine pathway and thereby has the potential of mediating N-methyl-D-aspartate neuronal damage and dysfunction[1][2]. Quinolinic acid (0-50 mM; 24 hours) decreases the percentage of survival cells ranging from 100±0.01% at 5 mM to 45.23±0.01% at 50 mM in N18D3 cells[2]. References: |