W-7 hydrochloride 是一种选择性钙调蛋白拮抗剂。 W-7 hydrochloride 抑制 Ca2+-钙调蛋白依赖性磷酸二酯酶和肌球蛋白轻链激酶，IC50 值分别为 28 μM 和 51 μM。 W-7 hydrochloride 可诱导细胞凋亡并具有抗肿瘤活性。
| Cas No. | 61714-27-0 |
| 别名 | N-(6-氨基己基)-5-氯-1-萘磺胺盐酸盐 |
| 化学名 | N-(6-aminohexyl)-5-chloronaphthalene-1-sulfonamide hydrochloride |
| Canonical SMILES | ClC1=C2C(C(S(=O)(NCCCCCCN)=O)=CC=C2)=CC=C1.Cl |
| 分子式 | C16H21ClN2O2S.HCl |
| 分子量 | 377.33 |
| 溶解度 | DMF: 20 mg/ml,DMSO: 14 mg/ml,DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml,Ethanol: 0.3 mg/ml |
| 储存条件 | Store at RT |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
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