(-)-Lobeline hydrochloride，一种烟碱样受体激动剂，在 α3β2 和 α4β2 神经元烟碱受体亚型中均是有效的拮抗剂。
| Cas No. | 134-63-4 |
| 别名 | 盐酸洛贝林; α-Lobeline hydrochloride; L-Lobeline hydrochloride |
| 化学名 | 2-((2S,6S)-6-((S)-2-hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone hydrochloride |
| Canonical SMILES | O[C@H](C1=CC=CC=C1)C[C@H]2N(C)[C@H](CC(C3=CC=CC=C3)=O)CCC2.Cl |
| 分子式 | C22H27NO2.HCl |
| 分子量 | 373.92 |
| 溶解度 | ≥ 74.8mg/mL in DMSO, ≥ 37.8mg/mL in Water with ultrasonic and warming, ≥ 37.5mg/mL in EtOH with ultrasonic |
| 储存条件 | Store at 4℃, protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Lobeline hydrochloride, a nicotinic receptor agonist, acting as a potent antagonist at both α3β2 and α4β2 neuronal nicotinic receptor subtypes. |
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