| CAS NO: | 88903-69-9 |
| 包装 | 价格(元) |
| 10ug | 电议 |
| 50ug | 电议 |
| 100ug | 电议 |
| 250ug | 电议 |
| Cas No. | 88903-69-9 |
| 别名 | XeC, Araguspongine E |
| 化学名 | [1R-(1R,4aR,11R,12aS,13S,16aS,23R,24aS)]-eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b1]dipyridine |
| Canonical SMILES | N12[C@@H]([C@@H](CCCCCC[C@@H]3O[C@@H]4N(CC3)CCC[C@@H]4CCCCCC5)CCC2)O[C@@H]5CC1 |
| 分子式 | C28H50N2O2 |
| 分子量 | 446.71 |
| 溶解度 | Slightly soluble in DMSO and Water |
| 储存条件 | Desiccate at -20°C,protect from light |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Xestospongin C is a marine natural product which was first isolated from Pacific basin sponges, and noted to have vasodilatory properties.[1] Xestospongin C antagonizes the calcium-releasing action of inositol-1,4,5-trisphosphate (IP3) at the receptor level. Inositol phosphates are important signal transduction messengers acting via IP3 receptors to promote the mobilization of Ca2+ from intracellular stores. Xestospongin C blocks the increase in intracellular calcium in vascular smooth muscle cells completely at a concentration of 25 μM.[2] Xestospongin C also inhibits the sarcoplasmic reticulum Ca2+ ATPase pump at concentrations of 700 nM.[3] Reference: |
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