Cholesterol-18O is the deuterium labeledCholesterol.Cholesterolis the major sterol in mammals and is makes up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons.Cholesterolplays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins^[1][2].Cholesterolis also an endogenous estrogen-related receptor α (ERRα) agonist^[3][4].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

388.65

C₂₇H₄₆¹⁸O

59613-51-3

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.