Cas No. | 66635-92-5 |
别名 | (1S)-5-苯基-2,3-二氢-1H-吡啶-1-羧酸,(-)-Ketorolac |
Canonical SMILES | O=C(C1=CC=C2N1CC[C@@H]2C(O)=O)C3=CC=CC=C3 |
分子式 | C15H13NO3 |
分子量 | 255.3 |
溶解度 | Chloroform: Slightly,Ethanol: >1mg/ml,Methanol: Slightly |
储存条件 | Store at -20°C |
General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
产品描述 | (S)-Ketorolac is a non-selective COX inhibitor and non-steroidal anti-inflammatory drug (NSAID; IC50s = 0.1 and 2.7 µM for COX-1 and COX-2, respectively). (S)-Ketorolac is approximately twice as potent as the racemic mixture and 60 times more potent than (R)-ketorolac in a rat pain assay. (S)-Ketorolac is cleared from rat kidney and liver more quickly than (R)-ketorolac. Formulations containing ketorolac have been used to manage postoperative pain as well as an ophthalmic solution to treat ocular pain and inflammation. |