| CAS NO: | 117423-74-2 |
| 包装: | 5mg |
| 市场价: | 2565元 |
| Cas No. | 117423-74-2 |
| 别名 | CGS 23131,SKF 107324 |
| 化学名 | 5-(3-carboxybenzoyl)-2-[[(5E)-6-(4-methoxyphenyl)-5-hexenyl]oxy]-benzenepropanoic acid |
| Canonical SMILES | COc1ccc(/C=C\CCCCOc2ccc(cc2CCC(=O)O)C(=O)c2cccc(c2)C(=O)O)cc1 |
| 分子式 | C30H30O7 |
| 分子量 | 502.6 |
| 溶解度 | ≤0.1mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide |
| 储存条件 | Store at -20℃ |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice All other available size: ship with RT , or blue ice upon request |
| 产品描述 | LY223982 is a potent and specific inhibitor of leukotriene B4 receptor, with an IC50 of 13.2 nM against [3H]LTB4 binding to LTB4 receptor. LY223982 is a potent and specific inhibitor of leukotriene B4 (LTB4) receptor, with an IC50 of 13.2 nM against [3H]LTB4 binding to LTB4 receptor. LY223982 is also a potent antagonist of the aggregation of human neutrophils by LTB4 (IC50, 100 nM)[1]. LY223982 inhibits transient leukopenia induced in rabbits with LTB4 (ED50, 3 mg/kg) but not with FMLP, and shows no agonist activity in any of the test systems[1]. References: |
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