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Tafamidis-d3
本产品不向个人销售,仅用作科学研究,不用于任何人体实验及非科研性质的动物实验。
Tafamidis-d3图片
包装与价格:
包装价格(元)
1mg电议
5mg电议

产品介绍
Tafamidis-d3 是 Tafamidis 氘代物。Tafamidis 是一种有效、选择性的transthyretin (TTR)稳定剂,对野生型 WT-TTR 和突变型同源四聚体 V30M-TTR,V122I-TTR 的活性相当,EC50值为 2.7-3.2 μM。Tafamidis 抑制淀粉样蛋白的生成
生物活性

Tafamidis-d3 is deuterium labeled Tafamidis. Tafamidis is a potent and selectivetransthyretin (TTR)stabilizer, shows comparable potency and efficacy to the mutumant homotetramers V30M-TTR, V122I-TTR and wild type WT-TTR, with EC50s of 2.7-3.2 μM. Tafamidis inhibits amyloidogenesis[1].

体外研究
(In Vitro)

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

分子量

311.13

Formula

C14H4D3Cl2NO3

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.