Kendomycin ((-)-TAN 2162) 是一种聚酮化合物抗生素，具有显着的抗菌和癌细胞细胞毒活性。
| Cas No. | 183202-73-5 |
| 别名 | (-)-TAN2162 |
| 化学名 | (13E)-6R,7S,8R,9R,10,11,12S,15,16S,17,18S,19S-dodecahydro-4,7,19-trihydroxy-2,6,8,12,14,16,18-heptamethyl-1,19:5R,9-diepoxybenzocyclooctadecen-3(5H)-one |
| Canonical SMILES | C[C@@H](CC[C@]1([H])[C@H](C)[C@H](O)[C@@H](C)[C@](O1)([H])C2=C(O)C3=O)/C=C(C[C@@H](C)C[C@H](C)[C@@]4(O)C=C2C(O4)=C3C)\C |
| 分子式 | C29H42O6 |
| 分子量 | 486.6 |
| 溶解度 | Soluble in DMSO |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Kendomycin is a macrolide from Streptomyces which displays potent cytotoxicity against several carcinoma cell lines (GI50< 100 nM). It also acts as an endothelin receptor antagonist and has antiosteoporotic activities. Certain effects are thought to be mediated through inhibition of proteasomal degradation of proteins. |
m.cnreagent.com