Echothiophate (iodide) 是一种有效的 hBChE（人丁酰胆碱酯酶）抑制剂。
| Cas No. | 513-10-0 |
| 别名 | 碘依可酯,Echothiophate iodide |
| 化学名 | 2-[(diethoxyphosphinyl)thio]-N,N,N-trimethyl-ethanaminium, monoiodide |
| Canonical SMILES | C[N+](C)(C)CCSP(OCC)(OCC)=O.[I-] |
| 分子式 | C9H23NO3PS.I |
| 分子量 | 383.2 |
| 溶解度 | DMSO: Slightly Soluble,Methanol: Slightly Soluble,Water: Slightly Soluble |
| 储存条件 | Store at -20°C |
| General tips | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. |
| Shipping Condition | Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request |
| 产品描述 | Echothiophate is an organophosphate and acetylcholinesterase (AChE) inhibitor. It is more active at ocular acetylcholinesterases than those isolated from rabbit brain, liver, or blood. In vivo, topical ocular administration of echothiophate (0.125 and 0.25% w/v) reduces intraocular pressure and induces miosis in dogs with normotensive eyes and those with inherited glaucoma. It also induces formation of subcapsular cataracts in cynomolgus monkeys. Formulations containing echothiophate have been used for the treatment of glaucoma. |
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