XEN723 is a novel and potent thiazolylimidazolidinone inhibitor ofStearoyl-CoA Desaturase(SCD1) withIC₅₀s of 45 and 524 nM in mouse and HepG2 cell, respectively.

IC50: 45 nM (SCD1 in Mouse), 524 nM (SCD1 in HepG2 cell)^[1]

XEN723 is a novel and potent thiazolylimidazolidinone inhibitor of Stearoyl-CoA Desaturase (SCD1) with IC₅₀s of 45 and 524 nM in mouse and HepG2 cell, respectively. XEN723 demonstrates an improvement in SCD1in vitropotency of more than 560-fold compare to the original high throughput screen (HTS) hit^[1].

425.48

Solid

C₂₁H₂₀FN₅O₂S

1072803-08-7

Room temperature in continental US; may vary elsewhere.

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

DMSO : 100 mg/mL(235.03 mM;Need ultrasonic)

请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80℃, 6 months; -20℃, 1 month (protect from light)。-80℃ 储存时，请在 6 个月内使用，-20℃ 储存时，请在 1 个月内使用。