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SCD1-IN-1
本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。
SCD1-IN-1图片
CAS NO:1111078-63-7
包装与价格：
包装价格(元)
100mg电议
250mg电议
500mg电议

产品介绍
SCD1-IN-1 是一种SCD1抑制剂 (IC50: 5.8 nM)。SCD1-IN-1 可用于皮肤病的研究。
生物活性

SCD1-IN-1 is aSCD1inhibitor (IC50: 5.8 nM). SCD1-IN-1 can be used in the research of dermatologic condition[1].

IC50& Target

SCD1[1].

体外研究
(In Vitro)

SCD1-IN-1 (compound I, 6 days) inhibits the SCD1 enzyme in intact human cells, with an IC50value of 6.8 nM[1].

体内研究
(In Vivo)

SCD1-IN-1 (compound I, 1.5% w/v, 25 μL, applied to surfaces of ears) reduces in cholesterol ester (CE) and wax ester (WE) production in hamster ear model[1].

Animal Model:Hamster ear model[1]
Dosage:1.5% in a vehicle of propylene glycol/transcutanol/ethanol 20/20/60, w/v, 25 μL.
Administration:Applied to ~3 cm2of the ventral surfaces of both the right and left ears, twice daily for 2 weeks.
Result:Resulted in a 62% reduction in CE and an 82% reduction in WE, a mechanism biomarker for sebum production in the hamster model, and a reduction in sebaceous gland size.
分子量

395.37

Formula

C20H20F3NO4

CAS 号

1111078-63-7

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.