SGK1-IN-3

立即咨询

SGK1-IN-3

本产品不向个人销售，仅用作科学研究，不用于任何人体实验及非科研性质的动物实验。

包装与价格：

产品介绍

SGK1-IN-3 (compound 3a) 是一种有效的、具有口服活性的SGK1抑制剂。丝氨酸/苏氨酸激酶 SGK1 是 β-连环蛋白途径的激活剂，是软骨降解的强大刺激剂，在患病的骨关节炎软骨中被发现在基因组控制下被上调。SGK1-IN-3具有研究骨关节炎的潜力。

生物活性	SGK1-IN-3 (compound 3a) is a potent and orally active inhibitor ofSGK1. Theserine/threonine kinaseSGK1 is an activator of theβ-cateninpathway and a powerful stimulator of cartilage degradation that is found to be upregulated under genomic control in diseased osteoarthritic cartilage. SGK1-IN-3 has the potential for the research of osteoarthritis^[1].
分子量	531.41
Formula	C₂₃H₂₀Cl₂N₆O₃S
运输条件	Room temperature in continental US; may vary elsewhere.
储存方式	Please store the product under the recommended conditions in the Certificate of Analysis.