CAS NO: | 62658-63-3 |
包装 | 价格(元) |
100mg | 电议 |
250mg | 电议 |
500mg | 电议 |
生物活性 | Bopindolol ((±)-Bopindolol) is an orally active antagonist ofβ-adrenoceptors (ARs)with partial agonist activity. Bopindolol is non-selective for β1- and β2-ARs and has low affinity for β3-AR subtype. Bopindolol has intrinsic sympathomimetic as well as membrane stabilizing actions, inhibitsreninsecretion, and interacts with5-HT receptors. Bopindolol is a prodrug ofPindolol(HY-B0982). Bopindolol can be used for essential and renovascular hypertension research[1][2][3][4]. | ||||||||
IC50& Target[1] |
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体内研究 (In Vivo) | Bopindolol (intravenous injection; 8, 16 and 32 μg/kg) causes a dose-dependent inhibition of isoprenaline-induced tachycardia, and this agent is 4 times more potent than propranolol in anaesthetised dogs[1].Bopindolol (0.3, 1 and 3 mg/kg; IP; single dosage) produces dose dependent decreases in diastolic blood pressure and in heart rate[2].
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分子量 | 380.48 | ||||||||
Formula | C23H28N2O3 | ||||||||
CAS 号 | 62658-63-3 | ||||||||
中文名称 | 波吲洛尔;吲苯脂心安 | ||||||||
运输条件 | Room temperature in continental US; may vary elsewhere. | ||||||||
储存方式 | Please store the product under the recommended conditions in the Certificate of Analysis. |