Racecadotril-d5 (Acetorphan-d5) is the deuterium labeled Racecadotril. Racecadotril (Acetorphan) is aneutral endopeptidase(NEP) inhibitor. Racecadotril and its active metabolite Thiorphan inhibits purified NEP activity from mouse brain withK_is of 4500 and 6.1 nM, , respectively. Antidiarrheal agent^[1].

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

390.51

C₂₁H₁₈D₅NO₄S

1246815-11-1

消旋卡多曲 d5

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.